research projects

Ongoing Research projects: Sponsored by Pakistan Medical Research Council

  1. Development of biopesticides for the control of dengue vector: 

    In last few decades, dengue has become a major health problem in tropical countries like Pakistan. Various methods have been employed to prevent the spread of dengue virus, among which there is currently no alternative for the vector control that mostly employs adulticide and larvicidal sprays of chemical and biological origin. However, synthetic chemicals have imparted several ecological and health problems, while bio-pesticides, on the other hand, are environmentally friendly and non toxic to non-target organisms. This inherent property of bio-pesticides can be utilized for the control of dengue vector i.e., Aedes aegypti by applying them in the insect rearing sites in the environment.

  2. Dengue fever epidemiology: 

    Dengue virus is endemic in Pakistan now, especially situation worsen each year after annual monsoon rain fall in the country. Previous studies from Pakistan, indicates change in demographic and clinical features of dengue fever over time. The current research is unable to make association of the demographic data with the severity of the disease. The data obtained from the current study may link certain patient’s characteristics with the severity of the disease. This study will open the door for the future studies focusing on finding the critical difference between the patients suffering from mild and sever disease.  

  3. Asymptomatic Dengue fever: a community study: 

    Morbidity and mortality rate due to dengue fever was very high in previous years and in next year the situation might be worse. Especially the risk of development of more severe form of dengue fever, i.e. dengue hemorrhagic fever and dengue shock syndrome, will be higher because of secondary infection with different serotypes of dengue virus circulating in the environment. Infected individuals who were diagnosed properly will be careful next year and try to prevent themselves from mosquito’s bite, as compared to those cases who were not screened. This study will reveal the asymptomatic dengue fever cases already present in the community who will be at risk of secondary infection, thus guiding the government policy makers to plan appropriate preventive measures. Moreover, diagnosed patients would be educated by delivering lectures and distributing handouts to them for the possible risk and preventive measures.

  4. Measles seroprevalence in children: